In the 1995 NCAA Tournament, #1-seeded UCLA was on the ropes against the 8th-seeded Missouri Tigers in the second round.
Down one point late in the game, Tyus Edney took matters into his own hands and carried his team to the Sweet 16. From there, the Bruins rolled to a national championship.
(Listen to Great Moments in Tournament History: Tyus Edney Goes Coast-to-Coast)
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