Wayne Rooney scored in the first half, but was sent off in the second as Manchester United held on with 10-men to defeat West Ham 2-1.
In derby action elsewhere, Liverpool and Everton played to a 1-1 draw thanks to Phil Jagielka’s late strike and Arsenal and Tottenham also drew 1-1 after Alex Oxlade-Chamberlain equalized for the Gunners.
League leaders Chelsea ran out comfortable 3-0 winners over Aston Villa and Manchester City defeated Hull 4-2.
Tom Rennie hosts a look back at all the best action from Game Week 6.
(Listen to the Barclays Premier League Highlights Show for 9/28/14)
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You can listen to EVERY Barclays Premier League game this season right here on WestwoodOneSports.com as well as on the TuneIn Radio App for mobile – search for ‘talkSPORT’.